| Archibald Garrod & the Black Urine Disease by Kristen Gabel & Douglas Allchin |
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VISUALS Title page London (Fleet Street), c. 1890 [by James Valentine; Wikipedia] Sherlock Holmes and Dr. Watson [Wikimedia] London's Tower Bridge, 1892 [Wikipedia] St. Bartholomew's Hospital, early 19th century [Wikimedia] Archibald Garrod, c.1908 hematoporphyrinuria chemical indicators (litmus and Benedict's solution) St. Bartholomew's lab, 1896 [Wellcome Trust] "peeing" fountain alkaptonuria homogentisic acid and tyrosine Table: Proportion of Alkaptonuric Members to Normal Members in 9 Families [Garrod, 1902, Table 2] Garrod Table: The large Proportion of Alkaptonurics Who Are the Offspring of Marriage of First Cousins [Garrod, 1902, Table 3] Hugo de Vries and Carl Correns, rediscoverers of wokr by Gregor Mendl starch grains in Round versus Wrinkled pea seeds [Gregory, 1903] Garrod & William Bateson Mendelians vs. Biometricians: Wm. Bateson & Reginald Punnett vs.Karl Pearson and Raphael Weldon Garrod, 1910 [Royal Society] St. Bartholomew consulting room [Wellcome Trust] albino sisters (Florence & Mary Martin) cystinuria [kidneyatlas.com] pentosuria & pedigrees (from 20th century) enzyme deficiency diseases Garrod, 1930s [Wellcome Trust] George Beadle [Caltech Archives] & Neurospora comparing Garrod & Beadle enzyme deficiency in alkaptonuria & gene locus on chromosome 3 genetic individuality Garrod & Inborn Errors of Metabolism